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Location, location, location: Even gut immune response is site-specific

Why is it that some chronic inflammatory bowel diseases, such as Crohn’s, affect both the small intestine and the colon, while others, like ulcerative colitis, are restricted to the colon? In order to solve clinical puzzles such as this one, among others, researchers from the University of W├╝rzburg created miniature versions of the digestive tract in the lab. One of their discoveries: the digestive tract contains an inherent segmentation that could shed new light onto these common inflammatory conditions.